New discovery solves problem of anti-inflammatory substance

There have been great expectations regarding the production of a drug to block the enzyme LTA4 hydrolase, which plays a key role in the body’s inflammatory response. However, in clinical trials, such molecules have proven to be only moderately effective. Now, researchers at Karolinska Institutet have successfully refined their understanding of why previous substances have been less effective — and in so doing have produced a molecule that gets around the problem.

Fuente : http://www.eurekalert.org/pub_releases/2014-03/ki-…