Understanding a protein’s role in familial Alzheimer’s disease

Researchers at the University of California, San Diego School of Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer’s disease, discovering that simple loss-of-function does not contribute to the inherited form of the neurodegenerative disorder.

Fuente : http://www.eurekalert.org/pub_releases/2013-11/uoc…